Revolutionizing Eye Care with Bona's Preservative-Free Multi-Dose Eye Dropper

As global demand for safer, more sustainable ophthalmic solutions grows, we’re proud to introduce our innovative Preservative-Free Multi-Dose (PFMD) eye dropper device — an advanced delivery system designed to protect eye health while eliminating the need for harmful preservatives.

Why Preservative-Free Matters

Traditional eye drops often rely on preservatives to prevent microbial contamination. However, long-term use of preservatives like benzalkonium chloride (BAK) has been linked to eye irritation, dry eye syndrome, and damage to the ocular surface — especially in patients with chronic conditions.

Our PFMD device solves this problem by offering a safe, reusable, and contamination-resistant solution — without the need for any added preservatives.

Key Benefits of Our PFMD Device

• Antibacterial Protection
  Successfully passed stringent microbial challenge tests, ensuring product sterility even after repeated use.
  
  
• Preservative-Free & Multi-Dose
  Allows for preservative-free formulations in a convenient, multi-dose format, reducing waste and cost.
  
  
• Patent-Screened Innovation
  The device has successfully passed patent screening, validating its novelty and protecting its design.
  
  
• Stability-Oriented System Design
  The system is designed with a metal-free liquid path to maintain the chemical stability of the formulation.
  
  
• Sustainable & Patient-Friendly
  Compact, easy to use, and eco-conscious — designed with both patients and planet in mind.
  
  
• Global Regulatory Compliance Overview
  Regulatory Compliance: EU, EP & USP Standards

How Our PFMD Ensures Microbial Protection

1. Spring-Sealed Outlet for Reliable Closure

At the core of our microbial protection is a precision-engineered spring mechanism. The tip of the dropper is sealed under continuous pressure exerted by a medical-grade spring. After each use, the spring force ensures that the tip seal returns to a fully closed position, minimizing the risk of microbial contamination from the environment. This mechanical seal eliminates the need for preservatives by preventing airborne pathogens and contact-based microorganisms from entering the liquid path.

2. Independent Air Return Channel to Prevent Backflow Contamination

Unlike conventional dropper systems, our design features an independent air return channel that allows pressure equalization without compromising sterility. The system is equipped with a dedicated air intake path integrated with a membrane filter, which permits only air to pass through while blocking microorganisms, effectively maintaining the sterility of the formulation.

Who Will Benefit?

• Patients with dry eye disease (DED) or ocular surface disorders
• Those managing glaucoma or allergies requiring frequent dosing
• Post-cataract or LASIK surgery patients needing sterile lubrication
• Contact lens users seeking preservative-free rewetting drops

The Future of Ophthalmic Primary Packaging

Our Preservative-Free Multidose (PFMD) system represents the next generation of ophthalmic primary packaging — combining advanced pharmaceutical packaging technology with a patient-centric design. It ensures microbial protection, formulation stability, and sustainable performance, all without the use of preservatives.

Whether for innovative new molecules or established formulations, the PFMD system offers a safe, reliable, and user-friendly solution for both clinical and at-home ophthalmic treatments.

Visit Bona Pharma at booth #8.0M30 at CPHI Worldwide (Frankfurt, Germany) in October to learn more about PFMD eye dropper devices and other healthcare packaging solutions.