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Aptar CSP Technologies – a leader in active packaging solutions that ensure product protection, enhance brand recognition and improve use experiences, and part of AptarGroup Inc – is presenting its Activ-Blister™ Solutions for the protection of moisture and oxygen-sensitive tablets and capsules, alongside FreeThink Technologies and its ASAPprime® technology for accelerated shelf-life determination. The combination is a “right the first time” approach to stability challenges and blister package design that virtually eliminates protracted testing and costly reformulations. The webinar, titled Rethinking Oral Solid Dose Packaging, will be conducted on March 28 at 11:00am EST.
Activ-Blister solutions control the internal atmosphere of individual blister cavities, allowing for improved product performance and enhanced shelf-life. Using proprietary three phase polymer technology, engineered materials can absorb customized amounts of water vapor, oxygen, and/or volatile compounds, and can be produced in shapes and sizes to accommodate any tablet and capsule size. This innovative technology can be applied via heat-staking, without the use of adhesives, and added to existing packaging lines.
Working together with FreeThink Technologies, a leader in accelerated shelf-life determination, and utilizing their ASAPprime technology, a drug product’s moisture and oxygen sensitivity is determined using highly accelerated stability studies open to specified environmental conditions – such as temperature, relative humidity and oxygen level. With this analysis, modeling creates a theoretical blister design with Activ-Blister solutions to achieve desired shelf life.
Once the optimized blister and sorbent are determined, laboratory, clinical and stability study packaged product can be manufactured. This total process from Aptar CSP Technologies is called Xcelerate and provides expedited end-to-end expertise for packaging of sensitive oral solid doses, from R&D to commercial launch.
The combination of Activ-Blister solutions and ASAPprime technology is in response to the increased complexity of matching moisture- and oxygen-sensitive oral dose products to ideal packaging solutions, as well as to the ever-growing demand to expedite time to market. Tablets and capsules are today’s most popular drug delivery forms, and stability issues are only likely to increase with the development of more potent API’s, larger molecules and modified release profiles. Innovative and evolving dosage forms, such as chewable and disintegrating tablets, also face heightened stability challenges and problems of shelf life. Adding to all of this, global distribution demands in zone 4a/4b (hot/humid) are also increasing.
“Activ-Blister solutions and the Xcelerate complete packaging service offer improved stability, extend shelf-life and expedite time to market for sensitive oral solid dose products,” said Craig Voellmicke, Vice President, Business Development, Aptar CSP Technologies. “Together, they provide a valuable combination of effective drug protection and ease of adoption.”
CSP Technologies, Inc. Introduces Material Science Lab in Newly Expanded Manufacturing Space
CSP Technologies, Inc. – a leader in designing and producing packaging solutions that ensure product protection, enhance brand recognition and improve consumer experiences – has completed a 100,000-square-foot facility expansion at its Auburn, Alabama headquarters, and is currently transitioning several new and enhanced capabilities into the ample space.
CSP Technologies, Inc. expanding Auburn, AL facility for increased manufacturing & warehousing space
CSP Technologies, Inc. is expanding its Auburn, Alabama manufacturing and warehousing capacity by 110,000 square feet. Construction of the new structure, located adjacent to the existing headquarters, is currently underway.
At Smart Packaging Conference in Germany, CSP Technologies, Inc. to present approach for enhancing shelf life for transdermal & oral solid dose drugs
François Bidet, Director of Business Development EMEA, CSP Technologies, to discuss benefits of company's patented engineered Activ-Polymer technology and Activ-Film materials for Headspace Management.
CSP Technologies' focus for enhancing the shelf life for transdermal and oral solid dose drugs
Despite being two very different drug delivery platforms, oral solid doses and transdermal patches can face similar packaging headspace challenges that impact shelf life; besides moisture and oxygen ingress, exposure to certain conditions can lead to the formation of volatile organic compounds (VOCs) and other gases that, in turn, may interact with drug products and capsules, adversely impacting their stability.
At IPA’s Stability Program Conference, CSP Technologies, Inc. to present approach for enhancing shelf life for transdermal & oral solid dose drugs
Craig Voellmicke, VP of Business Development, to discuss benefits of CSP’s patented engineered Activ-Polymer™ solutions for Headspace management at June conference in Montreal.
CSP takes its desiccant packaging concepts into new spaces, including new pharma blisters with desiccant foils
François Bidet, CSP's Director of Business Development for EMEA, sat down with us recently in order to review some of the company's latest offerings. Of special note is the company's upcoming Activ-Blister concept, which takes desiccant foils manufactured by the firm and applies them to blister packaging for pills and capsules.
CSP Technologies to showcase expanded options for Activ-Seal closures with desiccant technology
The original Activ-Seal closure incorporates moisture and gas scavenging technology which is press-fit into an induction-sealed, tamper-evident screw cap. Built directly into screw cap closure, effortless insertion technology controls levels of moisture and volatile off-gasses, helping to ensure product stability and extend shelf life.
CSP Technologies, Inc. introduces Activ-Blister™ solutions for customizable product protection at Interphex NYC
Packaging innovation protects solid dose pharmaceuticals from moisture, oxygen and odors while enhancing shelf life, eliminating purging/secondary packaging and enabling a move from bottles to blisters.
CSP Technologies, Inc. to acquire Maxwell Chase Technologies, LLC
On March 15th, 2016 CSP Technologies, Inc., a global leader in advanced polymeric protective packaging solutions, announced the acquisition of Maxwell Chase Technologies, LLC., a US-based producer of absorbent and non-absorbent packaging solutions for the food industry.
- Jo Webb
- Company News
- Created 11 Mar 2019
- Modified 11 Mar 2019
- Hits 99