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Preservatives in nasal formulations, such as Benzalkonium Chloride (BAC), can have a negative impact on the ciliated tissue in the nasal cavity. The side effects of preservatives often include irritation of the nasal passages, nose bleeding, allergic reactions and tissue thinning or damage.
The research shows that 80% of patients prefer preservative-free medications, also found that the vast majority of physicians and pharmacists prefer prescribing/recommending preservative-free medications. Consumer preference driving manufacturers to remove preservatives from formulations.
As a manufacturer specializing in Dosing Delivery Systems, Bona has launched a packaging system matching preservative free nasal spray preparations--Preservative free nasal pump.
1.Materials: The materials used for Preservative free nasal pumps are compliant with the regulatory requirements of the U.S. and EU Food Contact regulations and the U.S. and European Pharmacopoeias with regard to formulation contact requirements.
2.Dosages: 45mcl, 50mcl, 70mcl, 90mcl, 100mcl, 130mcl and 140mcl.
3.Bottles: 10ml, 20ml, 30ml, 40ml, 50ml, HDPE material Or matching customer's Plastic or Glass bottle.
4.Closure systems: 20mm Snap on, 18/415 screw on.
5.Tested to ensure full protection against microbial contamination. Clean room manufacturing, Gamma irradiation available.
6.Colors: Custom finger pad and cap colors available.
7.Filling lines: Normal snap on capping line, same dimensions as All plastic nasal pump.
8.Spray performance: Adjustable for different formulations.