Clariant Plastics & Coatings Healthcare Polymer Solutions recently launched static-reducing functional plastic compounds which, when used in drug delivery devices, enable increased dose reliability. The resins are part of the wider ‘medical grade’ MEVOPUR® line of color and additive concentrates and ‘ready-to-use’ polymer compounds, covering polymers from PE to PEEK.
Plastics are insulators, and therefore prone to build-up of static charges. In applications where plastics are in contact with powders, the powder can stick to the surface. In drug delivery devices, such as dry powder inhalers, this sticking effect reduces the dose reliability and repeatability. MEVOPUR permanent antistatic compounds reduce the surface resistivity and dissipate charges quickly, thereby eliminating sticking. However, since the plastics often have direct drug contact, and inhalation is considered as a medium-to-high risk drug administration route, the plastic materials need to be evaluated for biocompatibility and risk of potential leachables.
In a recent development program with a leading European pharmaceutical company, members of Clariant’s global Healthcare Polymer Solutions team provided technical support and compounded materials covering ABS, COP (cyclic olefin polymer) and PP resins that the development team planned to use. The critical areas in contact with the drug flow needed to avoid static charge build- up, and the MEVOPUR antistatic agent, combined with the chosen polymer, demonstrated antistatic functionality that significantly reduced this problem. In other development programs, antistatic functionality was combined with the chosen color in one compound product.
Although many resins are now widely available as ‘medical grade’ products with supporting regulatory declarations and change notification, this usually only covers the resin, and not colors or additives that are introduced by compounding or masterbatch concentrates. It is these colors and additives that present the higher risk of potential leachables that could end up in the drug. The problem is particularly acute as these added materials change routinely over the life time of the product.
The MEVOPUR family significantly reduces this risk by using pre-tested ingredients that support compliance to medical and pharmaceutical standards such as ISO10993 and USP Class VI, manufactured in EN- ISO13485:2016 certified production facilities and change control.
Other examples where MEVOPUR anti-static compounds are applied in drug delivery is in transparent plastic ‘spacer’ accessories used with metered-dose inhalers (MDI). These spacers which act as ‘accumulators’ to aid in correct dosing, are mainly used by very young or elderly patients who have difficulty to use an MDI unaided. Although anti-static functionality is needed, the materials used are often not ‘medical grade’, and so they can present the same risk as the described above. MEVOPUR antistatic compounds are available both in opaque colors and in transparent MABS (methyl methacrylate-acrylonitrile-butadiene-styrene) delivering the same quality and regulatory compliance.
“Recently, we introduced the theme of ‘The Color of Innovation” to show how early collaboration with Clariant’s expert team and applying QbD (Quality by Design) principles to material decisions, widen the scope of possibilities,” explains Steve Duckworth, Global Head of Marketing & Business Development- Healthcare. ‘This is about bringing new ideas and capabilities to designers, but without sacrificing on regulatory compliance. This is why we say that MEVOPUR helps make every decision an opportunity.”
Closer to Chinese customers from the start. Clariant’s Additives business continues to step up support for the needs of China’s growth industries, with new top-class facilities to foster R&D and joint application technology developments at the One Clariant Campus (OCC). Ahead of Chinaplas 2021, Clariant shares a taster of bio-based additives available to advance resource-efficient innovation in local market segments, highlights from its new sustainable solutions set for their regional debut.
DESVOCANT adsorbents are based on a naturally-occurring, non-toxic bentonite clay mineral with a unique surface structure, which is dried as granulate and contained in air-permeable sachets or bags. The adsorbents are available in a wide range of sizes suitable for placing in small product packages for shoes, handbags, or clothing, for example, through to full container loads of carpets, paints, toys, plastic packaging, pillows, mattresses, and furniture.
A team of experts from Clariant’s Business Unit Additives learned when working with a global film manufacturer that only a fraction of the plastic film scraps can be reused for production. To change this, they created AddWorks® PKG 906 Circle – a special polymer stabilizer able to substantially boost the rate of scrap reused in polyolefin films.
Clariant's next-generation dewaxing catalyst is used in pioneering plastic-to-diesel technology of Duslo’s research institute VUCHT. Proven economical conversion of plastic waste into fuel distillate encourages VUCHT to construct 40 MTA demonstration plant. The next-generation HYDEX E catalyst achieves excellent cold flow properties of distillate product, compliant with Euro 6 emission limits.
Clariant’s bio-based additives for biopolymers awarded OK compost INDUSTRIAL & OK biodegradable SOIL certification
Good news for the development of sustainable compostable products. Clariant’s bio-based processing & dispersing additives for biopolymers used in plastics have been awarded the “OK compost INDUSTRIAL” certificate. Awarding test and certification body, TÜV Austria Cert GmbH, also granted to Licocare RBW 102 Vita the “OK biodegradable SOIL” label, which is a key attribute for agricultural applications.
Clariant ColorWorks applies IR-detectable black technology to make other dark colors more recyclable
Clariant continues to develop new technology to improve the recyclability of plastics while offering packaging and product developers more color options. The latest development is a range of deep, dark colors that normally would have required the use of carbon black pigments that makes them undetectable by the near-infrared (NIR) sensors used in automated polymer sorting systems at recycling centers.
Clariant partners with Merck & SABIC to perfect laser marking of flexible packaging
Clariant has teamed up with pigment supplier Merck KGaA and resin producer SABIC to develop laser-marking technology and materials to ease the recycling process for flexible polyethylene (LDPE, LLDPE) packaging film. The results of the collaboration will be presented at K 2019, the international plastics trade fair being held on October 16 to 23 at Messe Dusseldorf in Germany.
Clariant advances a colorful future for biodegradable plastics
A colorful future is in reach for biodegradable plastics. Clariant brings it even closer with the launch of a range of 25 organic pigments for biodegradable and compostable polymers which are compliant with the European Norm 13432 opening up color options and the appeal of organically recyclable packaging.
Clariant additives enabling recyclability of plastics waste while sustaining valuable properties
Through a “Symphony of Collaboration” with partners along the full plastics value chain, Clariant is taking proactive steps in addressing the problem of plastic pollution with new solutions for diverse industry sectors, from packaging – the main use of plastics – to textile floorings and consumer electronics. Newly-developed AddWorks PKG 906 Circle for polyolefin films is a prime example of enabling plastic packaging producers to achieve some of their critical sustainability and business goals.
Clariant Hydrocerol Masterbatches cut plastic content in packaging by 10%
Packaging manufacturers and brand owners trying to reach sustainability goals and reduce costs are expressing keen interest in the newest HYDROCEROL chemical foaming agents (CFAs) from Clariant’s Masterbatches. The finer and more durable foam-cell structures make it possible to cut resin use and reduce part weight – without significant loss in mechanical properties.
Clariant partners with ExxonMobil and renewable energy group to advance Cellulosic Biofuel research
Clariant, a world leader in specialty chemicals, today announced that it has signed a joint research agreement with ExxonMobil and Renewable Energy Group (REG) to evaluate the potential use of cellulosic sugars from sources such as agricultural waste and residues to produce biofuel, which has the potential to play a role in reducing greenhouse gas emissions.
Clariant and Neste join forces to develop sustainable industrial solutions
Clariant, a world leader in specialty chemicals, has signed an agreement for a new partnership with Neste, the world’s leading provider of sustainable renewable diesel and an expert in delivering drop-in renewable chemical solutions.
Clariant unveils controlled-atmosphere packaging solutions
Clariant, a world leader in specialty chemicals, will present new products that help control moisture and prevent degradation of packaged pharmaceuticals at CPhI Middle East & Africa 2018. Clariant Healthcare Packaging is exhibiting its full range of desiccant canisters and packets, tubes and desiccant stoppers, oxygen scavengers, Advanced Desiccant Polymer (ADP®) and humidity stabilizers at Stand C25 at the trade show being held at the National Exhibition Center in Abu Dhabi, UAE, 3 - 5 September 2018.
Clariant introduces Humitector Type 2 non-reversible humidity indicator cards for SMD dry packing
Clariant, a world leader in specialty chemicals, and its Cargo & Device Protection unit, the originator of the color change humidity indicator card, introduce an industry-first innovation to better ensure that the integrity of dry packing that protects moisture-sensitive devices has not been compromised by high humidity at any time during shipment or storage. The new Humitector Type 2 Non-Reversible Humidity Indicator Cards are low-halogen and free of cobalt dichloride, a substance of concern to the European Chemical Bureau.
Clariant offers Sorb-It pharma desiccants for bulk pharmaceutical uses
Clariant, a world leader in Specialty Chemicals, and its Healthcare Packaging business line, introduce Sorb-It pharma desiccant bags, an enhanced line of desiccants that are now produced in new ISO 15378 GMP certified facilities to comply with global standards for primary pharmaceutical packaging.
Clariant, a world leader in specialty chemicals, is continuing the global rollout of its MEVOPUR®-LQ family of color and additive liquid masterbatches by featuring products for silicone elastomers at two important trade fairs: Pharmapack Europe 2017 in Paris (February 1-3) where Clariant is exhibiting on stand C35/C37, and MD&M West 2017 (booth #2450), which is being held in Anaheim, CA, February 7 - 9.
Clariant, a world leader in specialty chemicals, announces it will expand its plant in Lewiston, ME, and install a new compounding line to help meet growing demand for pre-colored medical plastic compounds that are supplied under the MEVOPUR® brand name. The new capacity will come on-line in Q4 2017.
Clariant, a world leader in specialty chemicals, will broaden its collaboration with Engineering Plastics division of Shinkong Synthetic Fibers Corp. to promote Clariant's non-halogenated flame retardants to a host of applications in China. Shinkong Engineering Plastics belongs to Taiwan’s top 3 enterprise, Shinkong Group. As a leading supplier of plastics, it serves various industries including electronics, home appliances and automotive etc. Its halogen-free compounds based on Clariant's flame retardants are experiencing rising demand as more and more OEM manufacturers in the electronics and electrical appliances industry eliminate components with bromine and PVC from their products because of tightening environmental regulations.
Clariant, a world leader in specialty chemicals, and its Healthcare Packaging unit, are announcing plans to install new, high-speed, six-color offset tube printing machines at Clariant’s production facility in Romorantin, France. The new equipment will increase capacity at the plant by an estimated 30 percent when the expansion is completed early in 2017.
Clariant introduces new liquid colors, additives for medical devices, pharmaceutical packaging
Clariant, a world leader in specialty chemicals, is introducing MEVOPUR®-LQ, a family of color and additive solutions that combines the benefits of the MEVOPUR ‘Controlled, Consistent and Compliant’ formulation and manufacturing approach with Clariant’s Hi Former® liquid-vehicle technology. The new products made their debut at CPhI / Innopak Europe, the global pharmaceutical event that took place in Barcelona.
- Nicole Tauster
- Company News
- Created 30 Jun 2020
- Modified 30 Jun 2020
- Hits 548