CD Formulation Documents

Active Pharmaceutical Ingredients (API) refer to the biologically active ingredients of pharmaceutical products. Excipients refer to inactive substances used as carriers or media for drugs or other active ingredients. Excipients are generally considered inactive, seemingly because they are only considered as ingredients for the production of tablets, creams or solutions. However, excipients usually play an important and active role in drugs, such as: helping to control the drug substance to meet the specific needs of bioavailability, assisting in binding and coating during the drug production process, and stable and unstable components, such as the use of Protein pigments and masks unpleasant tastes or odors, making it easy to identify different drugs by taste. Learn more at https://www.formulationbio.com/products/active-pharmaceutical-ingredient-excipients.html

Adsorbents and desiccants are usually placed in pharmaceutical packaging and are mainly used to control the content of moisture, oxygen, heptahydrate and impurities. Humectants are most commonly used in pharmaceutical formulations to control the moisture content of pharmaceutical dosage forms. CD Formulation provides customers with a variety of pharmaceutical excipients. Our pharmacy or other professional researchers and experimenters are constantly developing new product solutions. We can customize related products for customers, and also provide customers with drug development and research solutions. Learn more at https://www.formulationbio.com/products/adsorbents-desiccants-and-humectants.html

Amino Acid Series Active Pharmaceutical Ingredients: Amino acids are the building blocks of life, and they play a crucial role in many biological processes. Amino acid drugs are usually used as supplements of amino acids in the human body in the form of compound preparations. In addition, specific amino acids or their derivatives may also have specific pharmacological effects. CD Formulation provides a variety of amino acid series pharmaceutical active ingredients, and provides customized services according to customer needs.

As a supplier of pharmaceutical preparations, CD Formulation has pharmacy and other professional researchers and experimenters, and has extensive experience in drug development. Our company can customize the carrier material of the solid dispersion for the customer, and provide corresponding product solutions to facilitate the commercialization of the customer's drug. Learn more: https://www.formulationbio.com/amorphous-solutions-and-dispersions-technical-services.html

Antibacterial, Anti-inflammatory and Antiviral Series Active Pharmaceutical Ingredients: Antibacterial series can be divided into antifungal drugs and antibacterial drugs. Common antibacterial drugs include β-lactams, aminoglycosides, macrolides, quinolones, tetracyclines, and glycopeptides. Drugs for the treatment of systemic fungal infections include amphotericin B, azole derivatives, echinocandins, and flucytosine.

The Enhanced Bioavailability services provided by CD Formulation make us a leader in addressing issues of low solubility, low bioavailability and dissolution rates. Our end-to-end enhancement solutions combine the full capability to take a compound from concept to commercialization, minimizing project complexity, timelines and risk. Learn more: https://www.formulationbio.com/api-chemical-modification-services.html

Preformulation is a crucial phase in drug development in which the physicochemical profiling of active pharmaceutical ingredients (APIs) and excipients is determined and prototype formulations made. In the dosage form, the API is in direct contact with other components (excipients) in the formulation, thus facilitating drug administration and release and protecting it from environmental impacts. Although excipients are pharmacologically inert, they can interact with drugs in dosage forms, thereby affecting the stability of drugs in physical aspects, such as sensory properties, reduced dissolution or Chemically, which can cause drug degradation. The effective formulation requires careful selection of excipients to make it easy to administer, improve patient compliance, promote drug release and bioavailability, and extend its shelf life. Therefore, the compatibility screening of API with excipients or other active ingredients is considered as one of the essential parts in preformulation. Learn more at https://www.formulationbio.com/api-excipient-compatibility.html

To ensure the quality of your injectable drug formulations, medical devices, raw materials, excipients, water, water for injection, and APIs, CD Formulation's experts offer endotoxin detection and control testing. Your testing is performed for USP <85> bacterial endotoxin testing and USP <161> infusion and infusion components. Endotoxin testing requirements are specified for similar medical devices, including those that come into direct contact with blood or cerebrospinal fluid. Learn more at https://www.formulationbio.com/bacterial-endotoxin-testing.html.

To ensure the quality of your injectable drug formulations, medical devices, raw materials, excipients, water, water for injection, and APIs, CD Formulation's experts offer endotoxin detection and control testing. Your testing is performed for USP <85> bacterial endotoxin testing and USP <161> infusion and infusion components. Endotoxin testing requirements are specified for similar medical devices, including those that come into direct contact with blood or cerebrospinal fluid. Learn more: https://www.formulationbio.com/bacterial-endotoxin-testing.html

Cardiovascular Series Active Pharmaceutical Ingredients: There are many types of antihypertensive drugs, and different types of drugs have different curative effects on different types of hypertension. Antihypertensive drugs mainly affect blood pressure by affecting the sympathetic nervous system, the renin-angiotensin-aldosterone system and the endothelin system. Physiological regulation plays an important role in the system to play a hypotensive effect.

Chromatographic Analysis of Pharmaceutical Preparations：CD Formulation has developed a variety of detection methods and techniques for sample detection and analysis using chromatography to quantify and identify your substances and compounds from state-of-the-art facilities, while providing routine and advanced analysis down to ultra-trace levels testing to better help customers shorten time to market.

Tablet coating is one of the oldest pharmaceutical processes that still exist. Coating is a method of applying the outer layer of the essentially dry coating material to the surface of the dosage form to give specific benefits to the uncoated variety. Learn more at https://www.formulationbio.com/coated-tablets.html.

Compaction excipients are commonly used in solid dosage forms such as tablets, capsules and pills. If the powder cannot be compressed into a solid dosage form, compression can be enforced by adding an adhesive. Sometimes fillers are added before or after compaction to aid compaction. CD Formulation is a leading manufacturer of excipients that help improve the performance of pharmaceuticals and other products in the pharmaceutical industry. We develop, manufacture and market pharmaceutical excipients in solid, semi-solid and liquid dosage forms. If you have any requirements on excipients, please do not hesitate to contact us by phone or email in time, our colleagues will reply to you within 2-4 working days. Learn more at https://www.formulationbio.com/products/compaction-excipients.html

Controlled release excipients are an important research component in the pharmaceutical industry. The use of controlled release excipients can carry APIRs to specific parts of the body, thereby increasing the bioavailability of drugs and reducing side effects. Control of release behavior can be achieved by using polymer coatings on solid dosage forms or by adding various types of polymer matrix systems, enzyme activation systems, or systems that respond to changes in physical conditions in the formulation. Learn more: https://www.formulationbio.com/products/controlled-release-excipients.html

In the formulation and development of tablets, capsules, powders, creams, ointments and other dosage forms, Co-processed excipients has attracted more and more attention. It is different from physical mixtures. The physical mixture is a simple mixture that is processed by a small amount of excipients in a short period of time. However, in co-processed excipients, they have performance advantages that cannot be achieved using physical mixtures of the same excipient combination. Combining economical excipients with the optimal quantity of other functional materials will produce integrated products with superior functions than simple mixing of ingredients. Co-processed generally does not involve chemical changes. Learn more at https://www.formulationbio.com/products/co-processed-excipients.html

Controlled release excipients are an important research component in the The ingredients of cosmetic products are main ingredients and auxiliary ingredients. Cosmetics are chemically mixed substances made from natural, synthetic or extracted substances with different effects, processed through production procedures such as heating, stirring and emulsification. CD Formulation offers its customers active cosmetic ingredients for use in skin care cosmetics, color cosmetics, topical pharmaceutical cosmetics and liposomal sources. Learn more: https://www.formulationbio.com/products/cosmetic-ingredients.html

Cosmetic Preservatives:Preservatives are a class of ingredients that inhibit microbial activity and help keep products fresh and prevent deterioration. We use preservatives to help protect our products from bacteria, yeast and mold, and to maintain product stability.

Cosmetic Sweeteners: RUBUSOSIDE is a natural and highly effective sweetener: 300 times sweeter than sucrose, 1% of the calories of sucrose, with a refreshing sweetness close to sucrose, non-toxic side effects, with the effect of lowering blood lipids and blood sugar, etc. It is an ideal sweet substitute, widely used in beauty and cosmetic industries.

Detection of Fluorescent Whitening Agents in Pharmaceutical Packaging Materials: Fluorescent whitening agents (FWAs) are organic compounds that can absorb invisible ultraviolet light and excite visible blue-violet fluorescence, increasing the total amount of light reflection to achieve whitening and brightening effects. Numerous medical tests have proved that FWAs are potential carcinogenic factors and can be harmful to human health, while FWAs are also potentially harmful to the environment. Therefore, there is a need to test drug packaging materials for fluorescent whitening agents. CD Formulation can provide relevant testing services and test data to help customers provide safer and more environmentally friendly drug packaging and promote the process of drug commercialization.

Pharmaceutical formulations are composed of a biologically active primary drug and excipients with specific functions. Surfactants are the most common functional excipients, which changes the contact angle between the liquid and the tablet by reducing the interfacial tension, thus improving the hygroscopicity of the tablet. CD Formulation can test the contact angle of pharmaceutical excipients to help customers better select surfactants, which in turn facilitates drug development and facilitate the commercialization of pharmaceuticals. Learn more at https://www.formulationbio.com/determination-of-contact-angle-of-pharmaceutical-excipients.html.

Determination of Water Vapor Transmission Capacity of Pharmaceutical Packaging Materials: Water vapor transmission capacity refers to the amount of water vapor through the specimen in a certain period of time under the specified temperature, relative humidity, and certain water vapor pressure. The main role of the drug bottle is to protect the safety of drugs in the process of storage and transportation, to ensure the stability of the validity period. Water vapor transmission amount can reflect the barrier performance of the bottle, if this indicator exceeds the standard, it is easy to cause moisture in the long storage of drugs, affecting the safety of medication. Whether the water vapor transmission capacity of the bottle meets the standard is related to the purity of the raw materials used, the control of the production process, the quality of the mold and other factors, high-quality packaging is the key to protect the safety of drugs, but also an effective way to improve the added value of the product.

For your disinfectant or sanitizer efficacy studies, we can also perform simulation studies, hard surface testing, and testing under nominal conditions/procedures. CD Formulation has characterization of the disinfectant itself, and testing requirements vary by category, while disinfection products are related to consumer health and safety. Tests include active ingredient content determination, stability testing, pH determination, heavy gold measurement and microbial kill testing. Microbial kill tests may also include in vitro testing: time termination studies or suspension tests, specimen or carrier testing, environmental monitoring and in situ testing. Learn more at https://www.formulationbio.com/disinfection-efficacy-testing.html

Drug delivery system (DDS) is a technology system that comprehensively regulates the distribution of drugs in organisms in space, time and dose. Drug delivery system research includes not only the drug itself, but also the carrier materials and devices for the drug, as well as the technologies related to physicochemical modification and modification of the drug or carrier. By affecting the absorption, distribution, metabolism and elimination of drug compounds, various drug delivery technologies improve the therapeutic effect at the intended site of action while minimizing possible adverse effects. More at https://www.formulationbio.com/drug-delivery-system-services.html

In order to ensure the safety of drug product quality, the packaging system that comes into direct contact with the drug product needs to meet compatibility requirements. Compatibility studies refer to the process of evaluating packaging components or systems that are in direct contact with the drug product without serious, or unacceptable, changes in effectiveness and stability of drug products, or safety risks. CD Formulation offers services that include extractability studies of packaging materials or components, leaching studies of the effects of contact between the drug product and the packaging system, and possible effects on the drug product and excipient active ingredient adsorption studies. Learn more at: https://www.formulationbio.com/drug-formulation-and-packaging-compatibility.html

Inhalers are becoming more and more popular as an efficient method of drug delivery. The success of these devices largely depends on the excipients used to carry the active ingredients. Dry powder inhalers (DPI) rely on advanced and well-designed excipients to deliver the correct active ingredients in the correct quantity to the correct location. These new methods provide benefits to patients by providing a wider range of therapeutic DPI products and provide new opportunities for the continued development of dry powder inhalers. In dry powder inhalation (DPI), the fastest growing and most important form of inhalation therapy, the effectiveness of the drug absolutely depends on the excipients used to carry it. Larger excipient particles release much smaller active ingredient particles into the patient's lungs, while they themselves deposit harmlessly on the throat.

The elemental impurities in drugs are trace metals that can be found in final products, which may be harmful and must be controlled in the production process. The limits of drug elemental impurities are determined by the regulatory agencies of the corresponding countries/regions, such as the USP, ICH, Ph. Eur., ChP and JP. The sources of elemental impurities include raw materials, production process, packaging and container sealing system (CCS). They can interfere with the efficacy of drugs or have a direct toxic effect on patients. Therefore, the elemental impurities analysis of drugs is very important for drug quality control. CD Formulation laboratory is cGMP-compliant and equipped with state of the art analytical instruments. We have experienced analysis experts who can work with our formulation and manufacturing team to provide you with drug elemental impurities analysis services. Our elemental impurities analysis is performed in accordance with pharmacopeia methods to give you reliable, independent data, which can help you to make an appropriate risk assessment for your final drug products. In addition, we are also able to develop and validate tailored methods of elemental impurities analysis that will meet your specific needs. Learn more at https://www.formulationbio.com/elemental-impurities-analysis.html

Embryonic Microspheres Preparation: CD Formulation offers embryonic microsphere preparation services. Our pharmacology experts will customize a specific product to meet your needs. There is strict quality control on the size, shape, uniformity, of the microspheres to ensure that you get a high quality, stable and uniform product.

CD Formulation has been focused on the development of enteral nutrition formulations and technologies. We have established an end-to-end customer-centric formulation service platform, including development and production of pre-formulations to commercial formulations, with the aim of providing excellent project delivery. The dosage forms include the provision of development and manufacturing services for a wide range of conventional and complex formulations such as tablets, capsules, granules, and injectables. Learn more https://www.formulationbio.com/enteral-nutrition-formulation-development-solutions.html

Flavoring Chemical Agents: Due to the high cost or unavailability of natural flavor extracts, most commercial flavorings are "natural equivalents", meaning they are chemical equivalents of natural flavors, but are chemically synthesized rather than extracted from the raw material. Natural food ingredients such as raspberries can be identified using techniques such as headspace technology, so flavourists can use some of the same chemicals available to mimic the flavour.

According to the source of preservative substances, preservatives are generally divided into acid preservatives, ester preservatives, inorganic preservatives and biological preservatives. Food preservatives include parabens, benzoic acid, sodium benzoate, ethanol, sorbic acid, etc. The amount of various preservatives should not be too much to prevent harmful.

Cosmetic products such as shampoos, body washes, shaving creams and body lotions contain fragrance ingredients designed to enhance the user experience and even improve overall health. For example, scented soaps can encourage hand washing and better hygiene. Even products labeled as unscented may contain some fragrance ingredients to mask the undesirable odors of other ingredients.